CEBPE, CCAAT enhancer binding protein epsilon

CEBPE, CCAAT enhancer binding protein epsilon

• The protein encoded by this gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-delta. The encoded protein may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare congenital disorder. Multiple variants of this gene have been described, but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CCAAT/enhancer-binding protein epsilon, CCAAT/enhancer binding protein (C/EBP), epsilon, C/EBP-epsilon, CRP1, c/EBP epsilon,)
• NCBI Gene ID: 1053
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15744
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CCAAT enhancer binding protein epsilon interacts with:

• activating transcription factor 5
  ALX homeobox 4
  basic leucine zipper ATF-like transcription factor
  basic leucine zipper ATF-like transcription factor 2
  basic leucine zipper ATF-like transcription factor 3
  casein kinase 1 alpha 1 like
  CCAAT enhancer binding protein epsilon
  CCAAT enhancer binding protein gamma
  chaperonin containing TCP1 subunit 7
  COP9 signalosome subunit 3
  DENN domain containing 4A
  DNA damage inducible transcript 3
  E2F transcription factor 1
  ectodysplasin A2 receptor
  elongin B
  FOS like 1, AP-1 transcription factor subunit
  Fos proto-oncogene, AP-1 transcription factor subunit
  G protein-coupled receptor 22
  GATA binding protein 1
  general transcription factor IIA subunit 1 like
  heat shock protein 90 alpha family class A member 1
  interleukin 7
  Jun proto-oncogene, AP-1 transcription factor subunit
  lactotransferrin
  LDOC1 regulator of NFKB signaling
  lysine demethylase 2B
  mediator complex subunit 16
  MLLT6, PHD finger containing
  MYB proto-oncogene, transcription factor
  negative elongation factor complex member B
  nuclear factor of activated T cells 2
  phosphoserine aminotransferase 1
  POU class 2 homeobox 1
  protein inhibitor of activated STAT 1
  proteoglycan 2, pro eosinophil major basic protein
  RB transcriptional corepressor 1
  signal induced proliferation associated 1 like 1
  signal transducer and activator of transcription 6
  Spi-1 proto-oncogene
  TATA-box binding protein associated factor 5 like
  T-box transcription factor 2
  tribbles pseudokinase 1
  ubiquitin conjugating enzyme E2 I
  ZFP2 zinc finger protein
  zinc finger MYM-type containing 2
  zinc finger protein 384

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.