ZNF280B, zinc finger protein 280B

ZNF280B, zinc finger protein 280B

• The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. [provided by RefSeq, Jan 2015]

• Gene Synonyms (5'OY11.1, D87009.C22.3, SUHW2, ZNF279, ZNF632, zinc finger protein 280B, suppressor of hairy wing homolog 2, zinc finger protein 279, zinc finger protein 632,)
• NCBI Gene ID: 140883
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0D9SEJ8
  UNIPROT ID#>>B3KUN2
  UNIPROT ID#>>Q86YH2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

zinc finger protein 280B interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.