FCGRT, Fc fragment of IgG receptor and transporter

FCGRT, Fc fragment of IgG receptor and transporter

• This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

• Gene Synonyms (FCRN, alpha-chain, IgG receptor FcRn large subunit p51, Fc fragment of IgG, receptor, transporter, alpha, FcRn alpha chain, IgG Fc fragment receptor transporter alpha chain, heavy chain of the major histocompatibility complex class I-like Fc receptor, immunoglobulin receptor, intestinal, heavy chain, major histocompatibility complex class I-like Fc receptor, neonatal Fc receptor, neonatal Fc-receptor for Ig, transmembrane alpha chain of the neonatal receptor,)
• NCBI Gene ID: 2217
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024QZI2
  UNIPROT ID#>>P55899
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Fc fragment of IgG receptor and transporter interacts with:

• alpha 1,4-galactosyltransferase (P blood group)
  ANTXR cell adhesion molecule 1
  ATPase Na+/K+ transporting family member beta 4
  autophagy related 16 like 1
  beta-1,4-galactosyltransferase 5
  chromosome 1 open reading frame 112
  chromosome 3 open reading frame 52
  claudin 19
  component of oligomeric golgi complex 6
  decaprenyl diphosphate synthase subunit 1
  derlin 1
  dynein cytoplasmic 2 heavy chain 1
  exocyst complex component 7
  exportin 6
  FAM3 metabolism regulating signaling molecule C
  Fc fragment of IgG receptor and transporter
  fibroblast growth factor receptor 1
  fibroblast growth factor receptor 2
  fibroblast growth factor receptor 4
  furin, paired basic amino acid cleaving enzyme
  galanin and GMAP prepropeptide
  golgi integral membrane protein 4
  hemoglobin subunit alpha 2
  HGF activator
  integral membrane protein 2B
  IQ motif containing B1
  kinesin family member 14
  LDL receptor related protein 4
  LDL receptor related protein 5
  LDL receptor related protein 6
  low density lipoprotein receptor
  major histocompatibility complex, class I, B
  major histocompatibility complex, class I, E
  metadherin
  myelin protein zero like 1
  ninjurin 2
  non-SMC condensin I complex subunit D2
  peripheral myelin protein 22
  podocalyxin like 2
  protein tyrosine phosphatase receptor type S
  protocadherin 10
  protocadherin 7
  protocadherin gamma subfamily A, 11
  protogenin
  reticulon 4 receptor
  sarcoglycan epsilon
  secretoglobin family 1D member 1
  SH3 domain containing GRB2 like, endophilin B1
  solute carrier family 39 member 1
  sorting nexin 3
  thrombospondin 1
  timeless circadian regulator
  TNF superfamily member 9
  transmembrane protein 129, E3 ubiquitin ligase
  transmembrane protein 30B
  transportin 2
  transportin 3
  UL16 binding protein 2
  UL16 binding protein 3
  uroplakin 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.