FOXE1, forkhead box E1

FOXE1, forkhead box E1

• This intronless gene encodes a protein that belongs to the forkhead family of transcription factors. Members of this family contain a conserved 100-amino acid DNA-binding 'forkhead' domain. The encoded protein functions as a thyroid transcription factor that plays a role in thyroid morphogenesis. Mutations in this gene are associated with the Bamforth-Lazarus syndrome, and with susceptibility to nonmedullary thyroid cancer-4. [provided by RefSeq, Nov 2016]

• Gene Synonyms (FKHL15, FOXE2, HFKH4, HFKL5, NMTC4, TITF2, TTF-2, TTF2, forkhead box protein E1, HNF-3/fork head-like protein 5, forkhead box protein E2, forkhead, drosophila, homolog-like 15, forkhead-related protein FKHL15, thyroid transcription factor 2,)
• NCBI Gene ID: 2304
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O00358
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

forkhead box E1 interacts with:

• acidic nuclear phosphoprotein 32 family member C
  activity dependent neuroprotector homeobox
  A-kinase anchoring protein 8
  ALX homeobox 4
  AT-rich interaction domain 3B
  bromodomain adjacent to zinc finger domain 1A
  B-TFIID TATA-box binding protein associated factor 1
  DExD-box helicase 39A
  DNA ligase 3
  DNA polymerase epsilon, catalytic subunit
  far upstream element binding protein 3
  forkhead box K2
  GATA binding protein 4
  HEAT repeat containing 1
  helicase, lymphoid specific
  heterogeneous nuclear ribonucleoprotein L
  heterogeneous nuclear ribonucleoprotein U like 2
  high mobility group AT-hook 1
  homeobox A10
  homeobox B13
  homeobox B9
  homeobox C13
  homeobox D13
  karyopherin subunit alpha 1
  karyopherin subunit alpha 5
  karyopherin subunit alpha 6
  kinesin family member 22
  leucine rich repeats and WD repeat domain containing 1
  LIM domain binding 1
  macroH2A.1 histone
  macroH2A.2 histone
  methyl-CpG binding protein 2
  NOVA alternative splicing regulator 1
  nuclear factor I C
  origin recognition complex subunit 2
  origin recognition complex subunit 3
  paired box 3
  PBX homeobox 1
  PBX homeobox 2
  PBX homeobox 3
  PC4 and SFRS1 interacting protein 1
  PDS5 cohesin associated factor A
  phospholipase C beta 3
  RALY heterogeneous nuclear ribonucleoprotein
  Ran GTPase activating protein 1
  RecQ like helicase
  replication timing regulatory factor 1
  SATB homeobox 1
  SATB homeobox 2
  scribble planar cell polarity protein
  SIX homeobox 1
  spalt like transcription factor 1
  sphingomyelin phosphodiesterase 4
  structural maintenance of chromosomes 4
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
  symplekin
  transcription factor AP-2 alpha
  transcription factor AP-4
  transcription factor CP2
  upstream binding protein 1
  valyl-tRNA synthetase 1
  WIZ zinc finger
  zinc finger and BTB domain containing 34
  zinc finger MYM-type containing 4
  zinc finger RNA binding protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.