FLT3LG, fms related receptor tyrosine kinase 3 ligand

FLT3LG, fms related receptor tyrosine kinase 3 ligand

• Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]

• Gene Synonyms (FL, FLG3L, FLT3L, fms-related tyrosine kinase 3 ligand, flt3 ligand, fms related tyrosine kinase 3 ligand,)
• NCBI Gene ID: 2323
• Species: Homo sapiens (Human)
• UNIPROT ID#>>M0QYM9
  UNIPROT ID#>>P49771
  UNIPROT ID#>>B7ZLY4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

fms related receptor tyrosine kinase 3 ligand interacts with:

• fms related receptor tyrosine kinase 3 ligand
  keratin associated protein 5-9
  KIT ligand
  profilin 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.