DNAJC13, DnaJ heat shock protein family (Hsp40) member C13

DNAJC13, DnaJ heat shock protein family (Hsp40) member C13

• This gene encodes a member of the Dnaj protein family whose members act as co-chaperones of a partner heat-shock protein by binding to the latter and stimulating ATP hydrolysis. The encoded protein associates with the heat-shock protein Hsc70 and plays a role in clathrin-mediated endocytosis. It may also be involved in post-endocytic transport mechanisms via its associations with other proteins, including the sorting nexin SNX1. Mutations in this gene are associated with Parkinson's disease. [provided by RefSeq, Jun 2016]

• Gene Synonyms (PARK21, RME8, dnaJ homolog subfamily C member 13, DnaJ (Hsp40) homolog, subfamily C, member 13, DnaJ domain-containing protein RME-8, required for receptor-mediated endocytosis 8,)
• NCBI Gene ID: 23317
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75165
  UNIPROT ID#>>B3KN02
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DnaJ heat shock protein family (Hsp40) member C13 interacts with:

• BSCL2 lipid droplet biogenesis associated, seipin
  cyclic GMP-AMP synthase
  decapping enzyme, scavenger
  DnaJ heat shock protein family (Hsp40) member B11
  erythroid differentiation regulatory factor 1
  FYN binding protein 2
  HCLS1 associated X-1
  HSPA (Hsp70) binding protein 1
  interferon regulatory factor 2 binding protein 1
  junctophilin 4
  leucine rich repeat containing G protein-coupled receptor 4
  ligand dependent nuclear receptor interacting factor 1
  MANSC domain containing 1
  NOP9 nucleolar protein
  obscurin like cytoskeletal adaptor 1
  occludin
  pleckstrin homology domain containing A4
  pre-mRNA processing factor 3
  protein arginine methyltransferase 7
  regulatory factor X, 5 (influences HLA class II expression)
  ribosomal protein S6 kinase A6
  solute carrier family 39 member 9
  synaptonemal complex central element protein 2
  TMEM9 domain family member B
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.