GPR161, G protein-coupled receptor 161

GPR161, G protein-coupled receptor 161

• The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer. [provided by RefSeq, Mar 2017]

• Gene Synonyms (G-protein coupled receptor 161, G-protein coupled receptor RE2, RE2,)
• NCBI Gene ID: 23432
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0A0MQW8
  UNIPROT ID#>>Q8N6U8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

G protein-coupled receptor 161 interacts with:

• claudin 19
  G protein subunit beta 4
  junctophilin 1
  limb development membrane protein 1
  reticulon 4
  ubiquitin conjugating enzyme E2 Q1
  ubiquitin specific peptidase 12

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.