NR5A1, nuclear receptor subfamily 5 group A member 1

NR5A1, nuclear receptor subfamily 5 group A member 1

• The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. [provided by RefSeq, Jul 2008]

• Gene Synonyms (AD4BP, ELP, FTZ1, FTZF1, POF7, SF-1, SF1, SPGF8, SRXX4, SRXY3, hSF-1, steroidogenic factor 1, STF-1, adrenal 4 binding protein, fushi tarazu factor homolog 1, nuclear receptor AdBP4, steroid hormone receptor Ad4BP, steroidogenic factor 1 nuclear receptor, steroidogenic factor-1,)
• NCBI Gene ID: 2516
• Species: Homo sapiens (Human)
• UNIPROT ID#>>F1D8R8
  UNIPROT ID#>>Q13285
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nuclear receptor subfamily 5 group A member 1 interacts with:

• Aly/REF export factor
  C2 calcium dependent domain containing 6
  cullin 4B
  CXXC finger protein 1
  DExD-box helicase 39B
  DOT1 like histone lysine methyltransferase
  endothelial differentiation related factor 1
  eukaryotic translation initiation factor 4A3
  GATA binding protein 4
  general transcription factor IIB
  Janus kinase 3
  Jun proto-oncogene, AP-1 transcription factor subunit
  KRAS proto-oncogene, GTPase
  mitogen-activated protein kinase 1
  NCK adaptor protein 2
  N-terminal glutamine amidase 1
  nuclear factor kappa B subunit 2
  nuclear receptor coactivator 1
  nuclear receptor interacting protein 1
  nuclear transcription factor Y subunit alpha
  paired like homeodomain 1
  proline rich nuclear receptor coactivator 2
  prospero homeobox 1
  protein inhibitor of activated STAT 1
  protein kinase C zeta
  pyrimidinergic receptor P2Y6
  RAD54 like 2
  replication factor C subunit 5
  Sp1 transcription factor
  SRY-box transcription factor 2
  SRY-box transcription factor 8
  SRY-box transcription factor 9
  stathmin 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
  T-box transcription factor 19
  tektin 4
  THO complex 2
  trafficking protein particle complex 2
  transcriptional regulating factor 1
  ubiquitin conjugating enzyme E2 I
  zinc finger protein 653

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.