FUCA2, alpha-L-fucosidase 2

FUCA2, alpha-L-fucosidase 2

• This gene encodes a plasma alpha-L-fucosidase, which represents 10-20% of the total cellular fucosidase activity. The protein is a member of the glycosyl hydrolase 29 family, and catalyzes the hydrolysis of the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. This enzyme is essential for Helicobacter pylori adhesion to human gastric cancer cells. [provided by RefSeq, Aug 2010]

• Gene Synonyms (dJ20N2.5, plasma alpha-L-fucosidase, I+/--L-fucosidase 2, a-L-fucosidase 2, alpha-L-fucoside fucohydrolase 2, fucosidase, alpha-L- 2, plasma, plasma fucosidase,)
• NCBI Gene ID: 2519
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BTY2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

alpha-L-fucosidase 2 interacts with:

• claudin 12
  cullin 3
  F-box protein 6
  guanylyl cyclase domain containing 1
  heat shock protein family A (Hsp70) member 5
  homeobox A1
  keratin associated protein 10-1
  keratin associated protein 4-12
  keratin associated protein 5-2
  keratin associated protein 5-3
  late cornified envelope 1A
  late cornified envelope 1B
  late cornified envelope 1E
  late cornified envelope 4A
  mannosidase alpha class 2B member 2
  mesenchyme homeobox 2
  N-acetyltransferase 14 (putative)
  nuclear FMR1 interacting protein 2
  peptidylprolyl cis/trans isomerase, NIMA-interacting 1
  RAB21, member RAS oncogene family
  trans-golgi network vesicle protein 23 homolog C
  transportin 2
  ubiquinol-cytochrome c reductase hinge protein
  von Willebrand factor C domain containing 2
  Wnt family member 11

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.