- Gene Overview
- Interaction Network
- Sequence Verification
DNAH1, dynein axonemal heavy chain 1
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This gene encodes an inner dynein arm heavy chain that provides structural support between the radial spokes and the outer doublet of the sperm tail. Naturally occurring mutations in this gene are associated with primary ciliary dyskinesia and multiple morphological anomalies of the flagella that result in asthenozoospermia and male infertility. Mice with a homozygous knockout of the orthologous gene are viable but have reduced sperm motility and are infertile. [provided by RefSeq, Feb 2017]
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Gene Synonyms (dynein heavy chain 1, axonemal, axonemal beta dynein heavy chain 1, ciliary dynein heavy chain 1, dynein, axonemal, heavy polypeptide 1, heat shock regulated protein 1, testicular tissue protein Li 60, CILD37, DNAHC1, HDHC7, HL-11, HL11, HSRF-1, SPGF18, XLHSRF-1,)
- NCBI Gene ID:
25981
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q9P2D7
UNIPROT ID#>>A0A140VJI6
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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dynein axonemal heavy chain 1 interacts with:
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