HAVCR1, hepatitis A virus cellular receptor 1

HAVCR1, hepatitis A virus cellular receptor 1

• The protein encoded by this gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4, 12 and 19. [provided by RefSeq, Apr 2015]

• Gene Synonyms (CD365, HAVCR, HAVCR-1, KIM-1, KIM1, TIM, TIM-1, TIM1, TIMD-1, TIMD1, hepatitis A virus cellular receptor 1, T cell immunoglobin domain and mucin domain protein 1, T-cell immunoglobulin mucin family member 1, T-cell immunoglobulin mucin receptor 1, T-cell membrane protein 1, kidney injury molecule 1,)
• NCBI Gene ID: 26762
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96D42
  UNIPROT ID#>>B4DPB1
  UNIPROT ID#>>E9PFX0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

hepatitis A virus cellular receptor 1 interacts with:

• itchy E3 ubiquitin protein ligase
  Nedd4 family interacting protein 1
  phosphatidylinositol 4-kinase type 2 alpha
  semaphorin 4A
  sorting nexin 6
  ubiquilin 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.