ACAD8, acyl-CoA dehydrogenase family member 8

ACAD8, acyl-CoA dehydrogenase family member 8

• This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. The encoded protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine. Defects in this gene are the cause of isobutyryl-CoA dehydrogenase deficiency.[provided by RefSeq, Nov 2009]

• Gene Synonyms (ACAD-8, ARC42, IBDH, isobutyryl-CoA dehydrogenase, mitochondrial, activator-recruited cofactor 42 kDa component, acyl-Coenzyme A dehydrogenase family, member 8,)
• NCBI Gene ID: 27034
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UKU7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

acyl-CoA dehydrogenase family member 8 interacts with:

• abhydrolase domain containing 11
  acyl-CoA dehydrogenase family member 8
  DNA polymerase mu
  FAM161 centrosomal protein B
  lactate dehydrogenase D
  myotubularin related protein 14
  ras homolog family member U
  VPS37D subunit of ESCRT-I
  V-set and transmembrane domain containing 2A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.