GZMM, granzyme M

GZMM, granzyme M

• Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

• Gene Synonyms (granzyme M, HU-Met-1, Met-1 serine protease, lymphocyte met-ase 1, met-ase, natural killer cell granular protease, LMET1, MET1,)
• NCBI Gene ID: 3004
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P51124
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

granzyme M interacts with:

• ezrin
  nucleophosmin 1
  tubulin alpha 1b
  zinc finger protein 774

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.