INHA, inhibin subunit alpha

INHA, inhibin subunit alpha

• This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients. [provided by RefSeq, Aug 2016]

• Gene Synonyms (inhibin alpha chain, A-inhibin subunit, inhibin alpha subunit,)
• NCBI Gene ID: 3623
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P05111
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

inhibin subunit alpha interacts with:

• follistatin
  inhibin subunit beta A
  inhibin subunit beta B
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  siah E3 ubiquitin protein ligase 1
  transforming growth factor beta receptor 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.