KCNK3, potassium two pore domain channel subfamily K member 3

KCNK3, potassium two pore domain channel subfamily K member 3

• This gene encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene. [provided by RefSeq, Aug 2008]

• Gene Synonyms (K2p3.1, OAT1, PPH4, TASK, TASK-1, TASK1, TBAK1, potassium channel subfamily K member 3, TWIK-related acid-sensitive K(+) channel 1, TWIK-related acid-sensitive K+ 1, TWIK-related acid-sensitive K+ channel, acid-sensitive potassium channel protein TASK, acid-sensitive potassium channel protein TASK-1, cardiac potassium channel, potassium channel, two pore domain subfamily K, member 3, potassium inwardly-rectifying channel, subfamily K, member 3, two P domain potassium channel, two pore K(+) channel KT3.1, two pore potassium channel KT3.1,)
• NCBI Gene ID: 3777
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O14649
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

potassium two pore domain channel subfamily K member 3 interacts with:

• phosphatase and actin regulator 3
  S100 calcium binding protein A10
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.