MUC4, mucin 4, cell surface associated

MUC4, mucin 4, cell surface associated

• The major constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, are highly glycosylated proteins called mucins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. This gene encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of this gene have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats. [provided by RefSeq, Jul 2008]

• Gene Synonyms (ASGP, HSA276359, MUC-4, mucin-4, ascites sialoglycoprotein, mucin 4, tracheobronchial, pancreatic adenocarcinoma mucin, testis mucin, tracheobronchial mucin,)
• NCBI Gene ID: 4585
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0T3F4
  UNIPROT ID#>>Q99102
  UNIPROT ID#>>E9PDY6
  UNIPROT ID#>>A0A0G2JS65
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mucin 4, cell surface associated interacts with:

• mucin 4, cell surface associated
  polypeptide N-acetylgalactosaminyltransferase 11
  SUZ12 polycomb repressive complex 2 subunit

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.