PDC, phosducin

PDC, phosducin

• This gene encodes a phosphoprotein, which is located in the outer and inner segments of the rod cells in the retina. This protein may participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. It modulates the phototransduction cascade by interacting with the beta and gamma subunits of the retinal G-protein transducin. This gene is a potential candidate gene for retinitis pigmentosa and Usher syndrome type II. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

• Gene Synonyms (MEKA, PHD, PhLOP, PhLP, phosducin, 33 kDa phototransducing protein, G beta gamma binding protein, phosducin-like orphan protein,)
• NCBI Gene ID: 5132
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P20941
  UNIPROT ID#>>Q52LP8
  UNIPROT ID#>>A0A024R982
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosducin interacts with:

• cullin 4B
  proteasome 26S subunit, ATPase 5
  protein kinase cAMP-activated catalytic subunit alpha
  ring finger protein 123
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.