- Gene Overview
- Interaction Network
- Sequence Verification
PDE1C, phosphodiesterase 1C
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This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016]
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Gene Synonyms (calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C, 3',5'-cyclic-AMP phosphodiesterase, 3',5'-cyclic-GMP phosphodiesterase, Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A), phosphodiesterase 1C, calmodulin-dependent 70kDa, DFNA74, Hcam3, cam-PDE 1C, hCam-3,)
- NCBI Gene ID:
5137
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q14123
UNIPROT ID#>>A0A0A0MS69
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
phosphodiesterase 1C interacts with:
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this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
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