PGAM2, phosphoglycerate mutase 2

PGAM2, phosphoglycerate mutase 2

• Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). This gene encodes muscle-specific PGAM subunit. Mutations in this gene cause muscle phosphoglycerate mutase eficiency, also known as glycogen storage disease X. [provided by RefSeq, Sep 2009]

• Gene Synonyms (phosphoglycerate mutase 2, BPG-dependent PGAM 2, muscle-specific phosphoglycerate mutase, phosphoglycerate mutase 2 (muscle), phosphoglycerate mutase isozyme M, GSD10, PGAM-M, PGAMM,)
• NCBI Gene ID: 5224
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P15259
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphoglycerate mutase 2 interacts with:

• AAR2 splicing factor
  bromodomain containing 4
  clavesin 2
  dynein cytoplasmic 1 light intermediate chain 1
  katanin catalytic subunit A1 like 1
  nuclear transport factor 2
  phosphoglycerate mutase 2
  phosphoglycerate mutase family member 4
  thioredoxin
  tripartite motif containing 25
  ubiquitin C
  ubiquitin specific peptidase 15

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.