PLCB4, phospholipase C beta 4

PLCB4, phospholipase C beta 4

• The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010]

• Gene Synonyms (1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4, 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate, PLC-beta-4, dJ1119D9.2 (Phopholipase C, beta 4 (1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Beta 4)), inositoltrisphosphohydrolase, monophosphatidylinositol phosphodiesterase, phosphoinositidase C, phosphoinositide phospholipase C-beta-4, triphosphoinositide phosphodiesterase, ARCND2, PI-PLC,)
• NCBI Gene ID: 5332
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15147
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phospholipase C beta 4 interacts with:

• neuroligin 3
  REL proto-oncogene, NF-kB subunit

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.