ACKR3, atypical chemokine receptor 3

ACKR3, atypical chemokine receptor 3

• This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CMKOR1, CXC-R7, CXCR-7, CXCR7, GPR159, RDC-1, RDC1, atypical chemokine receptor 3, C-X-C chemokine receptor type 7, G protein-coupled receptor, G-protein coupled receptor 159, G-protein coupled receptor RDC1 homolog, chemokine (C-X-C motif) receptor 7, chemokine orphan receptor 1,)
• NCBI Gene ID: 57007
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P25106
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

atypical chemokine receptor 3 interacts with:

• HECT domain E3 ubiquitin protein ligase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.