PTHLH, parathyroid hormone like hormone

PTHLH, parathyroid hormone like hormone

• The protein encoded by this gene is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2). Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone. [provided by RefSeq, Nov 2013]

• Gene Synonyms (parathyroid hormone-related protein, PTH-rP, PTH-related protein, osteostatin, parathyroid hormone-like hormone preproprotein, parathyroid hormone-like related protein, BDE2, HHM, PLP, PTHR, PTHRP,)
• NCBI Gene ID: 5744
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RB29
  UNIPROT ID#>>P12272
  UNIPROT ID#>>Q53XY9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

parathyroid hormone like hormone interacts with:

• metadherin
  parathyroid hormone 1 receptor

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