SCN1B, sodium voltage-gated channel beta subunit 1

SCN1B, sodium voltage-gated channel beta subunit 1

• Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]

• Gene Synonyms (sodium channel subunit beta-1, sodium channel, voltage gated, type I beta subunit, sodium channel, voltage-gated, type I, beta, ATFB13, BRGDA5, EIEE52, GEFSP1,)
• NCBI Gene ID: 6324
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q07699
  UNIPROT ID#>>A0A1W2PR05
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

sodium voltage-gated channel beta subunit 1 interacts with:

• neurofascin
  sodium voltage-gated channel beta subunit 2

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