SLC1A2, solute carrier family 1 member 2

SLC1A2, solute carrier family 1 member 2

• This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2017]

• Gene Synonyms (excitatory amino acid transporter 2, excitotoxic amino acid transporter 2, glutamate/aspartate transporter II, sodium-dependent glutamate/aspartate transporter 2, solute carrier family 1 (glial high affinity glutamate transporter), member 2, EAAT2, EIEE41, GLT-1, HBGT,)
• NCBI Gene ID: 6506
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P43004
  UNIPROT ID#>>A2A2U1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

solute carrier family 1 member 2 interacts with:

• ajuba LIM protein
  solute carrier family 1 member 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.