- Gene Overview
- Interaction Network
- Sequence Verification
SERPINA7, serpin family A member 7
-
There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.[provided by RefSeq, Jun 2012]
-
Gene Synonyms (thyroxine-binding globulin, T4-binding globulin, mutant serpin family A member 7, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7, serpin A7, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7, thyroxin-binding globulin, TBG, TBGQTL,)
- NCBI Gene ID:
6906
- Species:
Homo sapiens (Human)
-
UNIPROT ID#>>P05543
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
serpin family A member 7 interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
|