TFDP1, transcription factor Dp-1

TFDP1, transcription factor Dp-1

• This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.[provided by RefSeq, Jan 2009]

• Gene Synonyms (transcription factor Dp-1, DRTF1-polypeptide 1, E2F dimerization partner 1, E2F-related transcription factor, down-regulated in liver cancer stem cells, DILC, DP1, DRTF1, Dp-1,)
• NCBI Gene ID: 7027
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14186
  UNIPROT ID#>>A0A024RDY4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transcription factor Dp-1 interacts with:

• A-kinase anchoring protein 8
  anaphase promoting complex subunit 5
  ATP synthase membrane subunit DAPIT
  chaperonin containing TCP1 subunit 5
  chaperonin containing TCP1 subunit 8
  chromatin licensing and DNA replication factor 1
  chromobox 1
  chromobox 1
  chromobox 3
  COMM domain containing 4
  COMM domain containing 6
  COMM domain containing 8
  copper metabolism domain containing 1
  cullin associated and neddylation dissociated 1
  ER lipid raft associated 2
  geminin DNA replication inhibitor
  golgi associated, gamma adaptin ear containing, ARF binding protein 1
  L3MBTL histone methyl-lysine binding protein 2
  L3MBTL2 polycomb repressive complex 1 subunit
  lin-37 DREAM MuvB core complex component
  lin-54 DREAM MuvB core complex component
  lin-9 DREAM MuvB core complex component
  MAX dimerization protein MGA
  Max protein
  MIER family member 2
  mindbomb E3 ubiquitin protein ligase 1
  multiciliate differentiation and DNA synthesis associated cell cycle protein
  neural proliferation, differentiation and control 1
  nucleoside-triphosphatase, cancer-related
  polycomb group ring finger 6
  pre-mRNA processing factor 31
  RING1 and YY1 binding protein
  SERTA domain containing 2
  suppressor of cytokine signaling 3
  TNFAIP3 interacting protein 2
  tripartite motif containing 28
  tubulin alpha 1c
  tumor protein p53
  tumor protein p53 binding protein 1
  WD repeat domain 5
  YY1 associated factor 2
  zinc finger RANBP2-type containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.