RNASEH2B, ribonuclease H2 subunit B

RNASEH2B, ribonuclease H2 subunit B

• RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). [provided by RefSeq, Nov 2008]

• Gene Synonyms (ribonuclease H2 subunit B, Aicardi-Goutieres syndrome 2 protein, RNase H2 subunit B, deleted in lymphocytic leukemia 8, ribonuclease HI subunit B, AGS2, DLEU8,)
• NCBI Gene ID: 79621
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5TBB1
  UNIPROT ID#>>Q8N451
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ribonuclease H2 subunit B interacts with:

• acidic nuclear phosphoprotein 32 family member E
  chromosome 1 open reading frame 52
  DAB2 interacting protein
  ribonuclease H2 subunit C
  zinc finger MYM-type containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.