SHOC2, SHOC2 leucine rich repeat scaffold protein

SHOC2, SHOC2 leucine rich repeat scaffold protein

• This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade. Mutations in this gene have been associated with Noonan-like syndrome with loose anagen hair. [provided by RefSeq, May 2010]

• Gene Synonyms (leucine-rich repeat protein SHOC-2, soc-2 suppressor of clear homolog, SIAA0862, SOC2, SUR8,)
• NCBI Gene ID: 8036
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UQ13
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

SHOC2 leucine rich repeat scaffold protein interacts with:

• DISC1 scaffold protein
  erbb2 interacting protein
  F-box and WD repeat domain containing 7
  HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
  leucine zipper like transcription regulator 1
  muscle RAS oncogene homolog
  phospholipase C like 2
  regulatory associated protein of MTOR complex 1
  Shoc2, leucine rich repeat scaffold protein
  SNW domain containing 1
  solute carrier family 35 member F5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.