POLR2M, RNA polymerase II subunit M

POLR2M, RNA polymerase II subunit M

• This gene encodes a subunit of a specific form of RNA polymerase II termed Pol II(G). The encoded protein may act as a negative regulator of transcriptional activation by the Mediator complex. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 4. Readthrough transcription between this gene and the neighboring upstream gene MYZAP (myocardial zonula adherens protein) is represented with GeneID 145781. [provided by RefSeq, Oct 2013]

• Gene Synonyms (protein GRINL1A, DNA-directed RNA polymerase II subunit M, isoforms 4/5, GRINL1A downstream protein Gdown4, glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A, polymerase (RNA) II (DNA directed) polypeptide M, polymerase (RNA) II subunit M, protein GRINL1A, isoforms 4/5, GCOM1, GRINL1A, Gdown, Gdown1,)
• NCBI Gene ID: 81488
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P0CAP1
  UNIPROT ID#>>P0CAP2
  UNIPROT ID#>>Q6EEV4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RNA polymerase II subunit M interacts with:

• ankyrin repeat and SOCS box containing 6
  copine 2
  leucine rich repeat kinase 2
  RNA binding motif protein 4B
  WD repeat domain 89
  WD repeat domain 92

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.