MADCAM1, mucosal vascular addressin cell adhesion molecule 1

MADCAM1, mucosal vascular addressin cell adhesion molecule 1

• The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

• Gene Synonyms (mucosal addressin cell adhesion molecule 1, MAdCAM-1, hMAdCAM-1, MACAM1,)
• NCBI Gene ID: 8174
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13477
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mucosal vascular addressin cell adhesion molecule 1 interacts with:

• ADP ribosylation factor guanine nucleotide exchange factor 2
  mucosal vascular addressin cell adhesion molecule 1
  transmembrane protein 97
  TRPM8 channel associated factor 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.