- Gene Overview
- Interaction Network
- Sequence Verification
PLA2G6, phospholipase A2 group VI
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The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010]
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Gene Synonyms (85/88 kDa calcium-independent phospholipase A2, 2-lysophosphatidylcholine acylhydrolase, 85 kDa calcium-independent phospholipase A2, GVI PLA2, iPLA2-beta, intracellular membrane-associated calcium-independent phospholipase A2 beta, neurodegeneration with brain iron accumulation 2, palmitoyl-CoA hydrolase, patatin-like phospholipase domain-containing protein 9, phospholipase A2, group VI (cytosolic, calcium-independent), CaI-PLA2, GVI, INAD1, IPLA2-VIA, NBIA2, NBIA2A, NBIA2B, PARK14, PLA2, PNPLA9, iPLA2, iPLA2beta,)
- NCBI Gene ID:
8398
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>O60733
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
phospholipase A2 group VI interacts with:
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this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
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