- Gene Overview
- Interaction Network
- Sequence Verification
IL18R1, interleukin 18 receptor 1
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The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
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Gene Synonyms (interleukin-18 receptor 1, CD218 antigen-like family member A, IL1 receptor-related protein, cytokine receptor, interleukin-18 receptor alpha, CD218a, CDw218a, IL-18R-alpha, IL-18Ralpha, IL-1Rrp, IL18RA, IL18Ralpha2, IL1RRP,)
- NCBI Gene ID:
8809
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q13478
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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interleukin 18 receptor 1 interacts with:
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