- Gene Overview
- Interaction Network
- Sequence Verification
SEMA3E, semaphorin 3E
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Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene encodes a class 3 semaphorin. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]
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Gene Synonyms (semaphorin-3E, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E, M-SEMAH, M-SemaK, SEMAH, coll-5,)
- NCBI Gene ID:
9723
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>O15041
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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semaphorin 3E interacts with:
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