SLC25A15, solute carrier family 25 member 15

SLC25A15, solute carrier family 25 member 15

• This gene is a member of the mitochondrial carrier family. The encoded protein transports ornithine across the inner mitochondrial membrane from the cytosol to the mitochondrial matrix. The protein is an essential component of the urea cycle, and functions in ammonium detoxification and biosynthesis of the amino acid arginine. Mutations in this gene result in hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome. There is a pseudogene of this locus on the Y chromosome.[provided by RefSeq, May 2009]

• Gene Synonyms (mitochondrial ornithine transporter 1, ornithine carrier 1, ornithine transporter 1, solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15, D13S327, HHH, LNC-HC, ORC1, ORNT1,)
• NCBI Gene ID: 10166
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y619
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

solute carrier family 25 member 15 interacts with:

• armadillo repeat containing 6
  developmental pluripotency-associated 3
  glycosylated lysosomal membrane protein
  ninein
  V-set and immunoglobulin domain containing 4
  zymogen granule protein 16B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.