ABCC4, ATP binding cassette subfamily C member 4

ABCC4, ATP binding cassette subfamily C member 4

• The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]

• Gene Synonyms (MOAT-B, MOATB, MRP4, multidrug resistance-associated protein 4, MRP/cMOAT-related ABC transporter, bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4), canalicular multispecific organic anion transporter (ABC superfamily), multi-specific organic anion transporter B,)
• NCBI Gene ID: 10257
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O15439
  UNIPROT ID#>>A8K2Q2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ATP binding cassette subfamily C member 4 interacts with:

• erbb2 interacting protein
  galectin 9C
  HCLS1 associated protein X-1
  pleckstrin homology domain containing A4
  sorting nexin 27
  transmembrane protein 128
  vir like m6A methyltransferase associated
  zinc finger and BTB domain containing 48

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.