APBB3, amyloid beta precursor protein binding family B member 3

APBB3, amyloid beta precursor protein binding family B member 3

• The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (FE65L2, SRA, amyloid-beta A4 precursor protein-binding family B member 3, FE65-like protein 2, amyloid beta (A4) precursor protein-binding, family B, member 3, amyloid precursor interacting protein, protein Fe65-like 2,)
• NCBI Gene ID: 10307
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96DX9
  UNIPROT ID#>>Q59EH2
  UNIPROT ID#>>O95704
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

amyloid beta precursor protein binding family B member 3 interacts with:

• COP9 signalosome subunit 4
  COP9 signalosome subunit 5
  COP9 signalosome subunit 6
  COP9 signalosome subunit 7A
  COP9 signalosome subunit 7B
  dual adaptor of phosphotyrosine and 3-phosphoinositides 1
  proteasome assembly chaperone 3
  RBM14-RBM4 readthrough
  Rho related BTB domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.