VPS26C, VPS26 endosomal protein sorting factor C

VPS26C, VPS26 endosomal protein sorting factor C

• The region of chromosome 21 between genes CBR and ERG (CBR-ERG region), which spans 2.5 Mb on 21q22.2, has been defined by analysis of patients with partial trisomy 21. It contributes significantly to the pathogenesis of many characteristics of Down syndrome, including morphological features, hypotonia, and cognitive disability. The DSCR3 (Down syndrome critical region gene 3) gene is found in this region and is predictated to contain eight exons. DSCR3 is expressed in most tissues examined. [provided by RefSeq, Jul 2008]

• Gene Synonyms (DCRA, DSCR3, DSCRA, vacuolar protein sorting-associated protein 26C, DSCR3 arrestin fold containing, Down syndrome critical region 3, Down syndrome critical region gene 3, Down syndrome critical region protein 3, Down syndrome critical region protein A,)
• NCBI Gene ID: 10311
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A8MTY9
  UNIPROT ID#>>O14972
  UNIPROT ID#>>A8MY26
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

VPS26 endosomal protein sorting factor C interacts with:

• 2,4-dienoyl-CoA reductase 2
  coiled-coil domain containing 22
  coiled-coil domain containing 93
  COMM domain containing 10
  COMM domain containing 3
  COMM domain containing 4
  COMM domain containing 6
  COMM domain containing 8
  copper metabolism domain containing 1
  DENN domain containing 10
  exportin 7
  inhibitor of CDK, cyclin A1 interacting protein 1
  ligand dependent nuclear receptor interacting factor 1
  mastermind like transcriptional coactivator 3
  meiotic double-stranded break formation protein 4
  pleckstrin homology domain containing A4
  protein tyrosine phosphatase non-receptor type 21
  RAB39B, member RAS oncogene family
  RAN binding protein 1
  SH3 domain containing GRB2 like, endophilin B1
  TEPSIN adaptor related protein complex 4 accessory protein
  VPS29 retromer complex component
  zinc finger containing ubiquitin peptidase 1
  zinc finger protein 655

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.