BTN3A3, butyrophilin subfamily 3 member A3

BTN3A3, butyrophilin subfamily 3 member A3

• The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A3) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM, Nov 2010]

• Gene Synonyms (BTF3, BTN3.3, butyrophilin subfamily 3 member A3, butyrophilin 3, butyrophilin subfamily 3 member A3 secreted isoform,)
• NCBI Gene ID: 10384
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O00478
  UNIPROT ID#>>A0A024R042
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

butyrophilin subfamily 3 member A3 interacts with:

• ADP ribosylation factor like GTPase 8B
  butyrophilin subfamily 3 member A2
  mucolipin 3
  OTU deubiquitinase with linear linkage specificity like
  tripartite motif containing 11

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.