RBM14, RNA binding motif protein 14

RBM14, RNA binding motif protein 14

• This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene. [provided by RefSeq, Oct 2011]

• Gene Synonyms (COAA, PSP2, SIP, SYTIP1, TMEM137, RNA-binding protein 14, RRM-containing coactivator activator/modulator, SYT-interacting protein, paraspeckle protein 2, synaptotagmin-interacting protein, transmembrane protein 137,)
• NCBI Gene ID: 10432
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0S2Z5V2
  UNIPROT ID#>>Q96PK6
  UNIPROT ID#>>A0A0S2Z4Z0
  UNIPROT ID#>>A0A0S2Z567
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RNA binding motif protein 14 interacts with:

• activator of transcription and developmental regulator AUTS2
  anterior gradient 2, protein disulphide isomerase family member
  autophagy and beclin 1 regulator 1
  autophagy related 16 like 1
  cell division cycle 37, HSP90 cochaperone
  centrosomal protein 250
  centrosomal protein 55
  coiled-coil domain containing 8
  COP9 signalosome subunit 5
  COP9 signalosome subunit 6
  cullin associated and neddylation dissociated 1
  cyclin dependent kinase 15
  cytokine receptor like factor 3
  DEAD-box helicase 17
  DEAD-box helicase 20
  DISC1 scaffold protein
  DMRT like family B with proline rich C-terminal 1
  drosha ribonuclease III
  ELL associated factor 1
  eukaryotic translation initiation factor 2 alpha kinase 1
  F-box protein 7
  FtsJ RNA 2'-O-methyltransferase 3
  fused in sarcoma
  G2 and S-phase expressed 1
  heterochromatin protein 1 binding protein 3
  heterogeneous nuclear ribonucleoprotein A0
  heterogeneous nuclear ribonucleoprotein A3
  heterogeneous nuclear ribonucleoprotein F
  HEXIM P-TEFb complex subunit 1
  histone deacetylase 11
  hook microtubule tethering protein 1
  hook microtubule tethering protein 3
  INO80 complex subunit B
  integrin alpha FG-GAP repeat containing 1
  KH RNA binding domain containing, signal transduction associated 2
  kinesin associated protein 3
  kinesin light chain 4
  La ribonucleoprotein 7, transcriptional regulator
  mediator complex subunit 4
  methyltransferase like 14
  mitogen-activated protein kinase 15
  NFKB inhibitor delta
  ninein
  nuclear assembly factor 1 ribonucleoprotein
  nuclear receptor coactivator 6
  nudE neurodevelopment protein 1 like 1
  obscurin like cytoskeletal adaptor 1
  par-6 family cell polarity regulator gamma
  pleckstrin homology domain containing A4
  PR/SET domain 16
  pre-mRNA processing factor 19
  pre-mRNA processing factor 6
  protection of telomeres 1
  PTEN induced kinase 1
  ribosomal L1 domain containing 1
  ribosome biogenesis regulator 1 homolog
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  ring finger protein 31
  RNA binding motif protein 25
  RNA binding motif protein X-linked
  RNA binding protein with serine rich domain 1
  Sad1 and UNC84 domain containing 2
  Sec24 related gene family, member C (S. cerevisiae)
  serine and arginine rich splicing factor 10
  SLAIN motif family member 1
  SMAD specific E3 ubiquitin protein ligase 2
  splicing factor 3b subunit 1
  stromal antigen 2
  SUZ12 polycomb repressive complex 2 subunit
  TATA-box binding protein associated factor 15
  TNFAIP3 interacting protein 2
  trans-golgi network protein 2
  tRNA methyltransferase subunit 11-2
  USO1 vesicle docking factor
  WD repeat domain 77
  WW domain containing E3 ubiquitin protein ligase 2
  zinc finger and BTB domain containing 10
  zinc finger CCCH-type containing 18

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.