SYNCRIP, synaptotagmin binding cytoplasmic RNA interacting protein

SYNCRIP, synaptotagmin binding cytoplasmic RNA interacting protein

• This gene encodes a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 20. [provided by RefSeq, Dec 2011]

• Gene Synonyms (GRY-RBP, GRYRBP, HNRNPQ, HNRPQ1, NSAP1, PP68, hnRNP-Q, heterogeneous nuclear ribonucleoprotein Q, NS1-associated protein 1, glycine- and tyrosine-rich RNA-binding protein,)
• NCBI Gene ID: 10492
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7Z645
  UNIPROT ID#>>O60506
  UNIPROT ID#>>Q59GL1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

synaptotagmin binding cytoplasmic RNA interacting protein interacts with:

• 5'-3' exoribonuclease 1
  AAR2 splicing factor
  angel homolog 2
  ankyrin repeat domain 11
  anterior gradient 2, protein disulphide isomerase family member
  APOBEC1 complementation factor
  apolipoprotein B mRNA editing enzyme catalytic subunit 3D
  aprataxin
  bridging integrator 3
  bromodomain containing 7
  cap methyltransferase 1
  centromere protein V
  centrosomal protein 55
  checkpoint kinase 2
  coiled-coil domain containing 137
  coiled-coil domain containing 59
  coiled-coil domain containing 8
  COP9 signalosome subunit 5
  COP9 signalosome subunit 6
  cullin associated and neddylation dissociated 1
  DEAD-box helicase 17
  DEAD-box helicase 24
  DEAD-box helicase 27
  DEAD-box helicase 42
  DEAD-box helicase 54
  defective in cullin neddylation 1 domain containing 1
  dicer 1, ribonuclease III
  DISC1 scaffold protein
  DnaJ heat shock protein family (Hsp40) member A4
  DOT1 like histone lysine methyltransferase
  dual specificity phosphatase 14
  EBNA1 binding protein 2
  eEF1A lysine and N-terminal methyltransferase
  engulfment and cell motility 3
  expressed sequence AI837181
  family with sequence similarity 120A
  Fas associated factor 1
  F-box and WD repeat domain containing 11
  F-box DNA helicase 1
  F-box protein 6
  fibronectin type III domain containing 3A
  GAR1 ribonucleoprotein
  heterogeneous nuclear ribonucleoprotein A0
  heterogeneous nuclear ribonucleoprotein A3
  heterogeneous nuclear ribonucleoprotein U like 1
  HEXIM P-TEFb complex subunit 1
  HMG-box transcription factor 1
  hyaluronan binding protein 4
  IKBKB interacting protein
  immunoglobulin superfamily member 8
  importin 4
  influenza virus NS1A binding protein
  insulin like growth factor 2 mRNA binding protein 1
  integrator complex subunit 7
  integrin alpha FG-GAP repeat containing 1
  interactor of little elongation complex ELL subunit 2
  jun B proto-oncogene
  kelch like family member 3
  KH RNA binding domain containing, signal transduction associated 1
  KH RNA binding domain containing, signal transduction associated 2
  KH RNA binding domain containing, signal transduction associated 3
  kinesin family member 21B
  Kruppel like factor 16
  La ribonucleoprotein 7, transcriptional regulator
  LEM domain nuclear envelope protein 2
  LSM14A mRNA processing body assembly factor
  LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated
  LUC7 like
  LUC7 like 2, pre-mRNA splicing factor
  lysine rich nucleolar protein 1
  mab-21 like 2
  maelstrom spermatogenic transposon silencer
  mediator complex subunit 13L
  methylphosphate capping enzyme
  methyltransferase like 14
  methyltransferase like 3
  microtubule actin crosslinking factor 1
  microtubule associated protein 1S
  mitochondrial ribosomal protein L50
  mitochondrial ribosomal protein S28
  mortality factor 4 like 1
  Myb related transcription factor, partner of profilin
  myosin light chain 12A
  N-acetyltransferase 10
  negative elongation factor complex member B
  neural precursor cell expressed, developmentally down-regulated gene 1
  NFKB activating protein
  NHL repeat containing 2
  NOP10 ribonucleoprotein
  NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase
  nuclear cap binding protein subunit 2
  nuclear protein 1, transcriptional regulator
  nuclear transcription factor-Y gamma
  obscurin like cytoskeletal adaptor 1
  patatin like phospholipase domain containing 8
  pentatricopeptide repeat domain 3
  peptidylprolyl isomerase like 1
  peptidylprolyl isomerase like 3
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  plexin A3
  poly(A) binding protein cytoplasmic 1
  poly(A) binding protein interacting protein 1
  poly(U) binding splicing factor 60
  potassium channel tetramerization domain containing 10
  pre-mRNA processing factor 40 homolog A
  pre-mRNA processing factor 8
  prostaglandin reductase 2
  protein arginine methyltransferase 8
  PTEN induced kinase 1
  Rac GTPase activating protein 1
  RALY heterogeneous nuclear ribonucleoprotein
  RBMX like 1
  RCC1 like
  ribosomal protein L26 like 1
  ribosomal protein S27 like
  ribosomal RNA processing 15 homolog
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  RIO kinase 1
  RNA pseudouridine synthase D4
  RNA transcription, translation and transport factor
  serine/arginine repetitive matrix 2
  SET binding factor 2
  SET domain containing 1B, histone lysine methyltransferase
  sirtuin 6
  sirtuin 7
  SMAD specific E3 ubiquitin protein ligase 1
  SNW domain containing 1
  solute carrier family 25 member 25
  splicing factor 3b subunit 3
  SprT-like N-terminal domain
  stomatin like 2
  STT3 oligosaccharyltransferase complex catalytic subunit B
  synaptotagmin 11
  synaptotagmin 2
  synaptotagmin 3
  synaptotagmin 8
  synaptotagmin 9
  talin 2
  TAR DNA binding protein
  TBC1 domain family member 10B
  thioredoxin like 4A
  THUMP domain containing 1
  TNFAIP3 interacting protein 2
  translocase of inner mitochondrial membrane 50
  transmembrane protein 177
  TRIO and F-actin binding protein
  tRNA methyltransferase subunit 11-2
  U2 small nuclear RNA auxiliary factor 2
  ubiquitin conjugating enzyme E2 S
  ubiquitin specific peptidase 32
  UFM1 specific peptidase 2
  UHRF1 binding protein 1
  UTP3 small subunit processome component
  UV stimulated scaffold protein A
  uveal autoantigen with coiled-coil domains and ankyrin repeats
  vir like m6A methyltransferase associated
  WD repeat domain 76
  WD repeat domain 77
  WD repeat domain 91
  WW domain containing E3 ubiquitin protein ligase 2
  Y box protein 1
  yippee like 5
  YTH N6-methyladenosine RNA binding protein 1
  zinc finger CCCH-type containing 8
  zinc finger protein 169
  zinc finger protein 286A
  zinc finger protein 598, E3 ubiquitin ligase
  zinc finger protein 746

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.