CLCN5, chloride voltage-gated channel 5

CLCN5, chloride voltage-gated channel 5

• This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]

• Gene Synonyms (H(+)/Cl(-) exchange transporter 5, chloride channel, voltage-sensitive 5, chloride transporter ClC-5, voltage-gated chloride ion channel CLCN5, CLC5, CLCK2, ClC-5, DENTS, NPHL1, NPHL2, XLRH, XRN, hCIC-K2,)
• NCBI Gene ID: 1184
• Species: Homo sapiens (Human)
• UNIPROT ID#>>V9GYG7
  UNIPROT ID#>>B3KRR2
  UNIPROT ID#>>A8K4H5
  UNIPROT ID#>>P51795
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

chloride voltage-gated channel 5 interacts with:

• BAG cochaperone 3
  epidermal growth factor receptor
  galectin 8
  membrane associated guanylate kinase, WW and PDZ domain containing 1
  neurotrophic receptor tyrosine kinase 1
  TMEM9 domain family member B
  vir like m6A methyltransferase associated
  WW domain containing E3 ubiquitin protein ligase 1
  WW domain containing E3 ubiquitin protein ligase 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.