- Gene Overview
- Interaction Network
- Sequence Verification
DNAJC24, DnaJ heat shock protein family (Hsp40) member C24
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Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008]
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Gene Synonyms (DPH4, JJJ3, ZCSL3, dnaJ homolog subfamily C member 24, 1700030A21Rik, CSL-type zinc finger-containing protein 3, DPH4 homolog (JJJ3, S. cerevisiae), DPH4, JJJ3 homolog, DnaJ (Hsp40) homolog, subfamily C, member 24, diphthamide biosynthesis protein 4, zinc finger, CSL domain containing 3, zinc finger, CSL-type containing 3,)
- NCBI Gene ID:
120526
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q6P3W2
UNIPROT ID#>>A0A0A0MT77
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
DnaJ heat shock protein family (Hsp40) member C24 interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
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