Col5a2, collagen, type V, alpha 2

Col5a2, collagen, type V, alpha 2

• This gene encodes the alpha-2 subunit of type V collagen, one of the low abundance fibrillar collagens that gets incorporated into growing fibrils with type I collagen. The encoded protein, in association with alpha-1 and/or alpha-3 subunits, forms homo- or heterotrimeric type V procollagen that undergoes proteolytic processing. Mice lacking the encoded protein die in utero. Transgenic mice that produce a structurally abnormal form of the encoded protein survive poorly and exhibit skin fragility, skeletal abnormalities and alterations in the collagen fiber organization. [provided by RefSeq, Dec 2015]

• (No alternate names found)
• NCBI Gene ID: 12832
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>Q3U962
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

collagen, type V, alpha 2 interacts with:

• a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
  collagen, type I, alpha 2
  FK506 binding protein 7
  matrix metallopeptidase 2
  peroxidasin
  SMAD family member 2
  SMAD family member 3
  SMAD family member 7

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.