DRAM2, DNA damage regulated autophagy modulator 2

DRAM2, DNA damage regulated autophagy modulator 2

• The protein encoded by this gene binds microtubule-associated protein 1 light chain 3 and is required for autophagy. Defects in this gene are a cause of retinal dystrophy. In addition, two microRNAs (microRNA 125b-1 and microRNA 144) can bind to the mRNA of this gene and produce the disease state. [provided by RefSeq, Mar 2017]

• Gene Synonyms (CORD21, PRO180, TMEM77, WWFQ154, DNA damage-regulated autophagy modulator protein 2, damage regulated autophagy modulator 2, transmembrane protein 77,)
• NCBI Gene ID: 128338
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6UX65
  UNIPROT ID#>>A0A024R0B7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DNA damage regulated autophagy modulator 2 interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.