TOM1L2, target of myb1 like 2 membrane trafficking protein

TOM1L2, target of myb1 like 2 membrane trafficking protein

• This gene belongs to a small gene family whose members have an N-terminal VHS domain followed by a GAT domain; domains which typically participate in vesicular trafficking. The canonical protein encoded by this gene also has a C-terminal clathrin binding motif. This protein has been shown to interact with Tollip, clathrin and ubiquitin and is thought to play a role in endosomal sorting. This gene resides in the 3.7 Mb deletion of chromosome region 17p11.2 that is associated with Smith-Magenis syndrome. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Apr 2017]

• Gene Synonyms (TOM1-like protein 2, target of Myb-like protein 2, target of myb1-like 2,)
• NCBI Gene ID: 146691
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7Z2U2
  UNIPROT ID#>>Q6ZVM7
  UNIPROT ID#>>B7Z671
  UNIPROT ID#>>F5H3S6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

target of myb1 like 2 membrane trafficking protein interacts with:

• CUE domain containing 1
  family with sequence similarity 9 member B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.