CTSV, cathepsin V

CTSV, cathepsin V

• The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011]

• Gene Synonyms (cathepsin L2, cathepsin L2, preproprotein, cathepsin U, CATL2, CTSL2, CTSU,)
• NCBI Gene ID: 1515
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R141
  UNIPROT ID#>>B2R717
  UNIPROT ID#>>O60911
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

cathepsin V interacts with:

• centrosomal protein 135
  coiled-coil domain containing 103
  DEAD-box helicase 19B
  defensin alpha 1
  estrogen receptor 2
  ferritin heavy chain 1
  glycoprotein integral membrane 1
  killer cell immunoglobulin like receptor, three Ig domains and short cytoplasmic tail 1
  kininogen 1
  L-2-hydroxyglutarate dehydrogenase
  major histocompatibility complex, class II, DP beta 1
  multimerin 1
  natriuretic peptide A
  polo like kinase 2
  pre-mRNA processing factor 8
  RAB28, member RAS oncogene family
  RNA binding fox-1 homolog 1
  signal sequence receptor subunit 4
  TBC1 domain family member 22B
  vanin 2
  Zic family member 1
  zinc finger and SCAN domain containing 12

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.