PPM1L, protein phosphatase, Mg2+/Mn2+ dependent 1L

PPM1L, protein phosphatase, Mg2+/Mn2+ dependent 1L

• The protein encoded by this gene is a magnesium or manganese-requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal-regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus. Finally, this gene may be involved in adiposity since it is upregulated in adipose tissues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

• Gene Synonyms (protein phosphatase 1L, PP2C epsilon, Protein phosphatase 2C epsilon isoform, protein phosphatase 2C isoform epsilon, PP2C-epsilon, PP2CE, PPM1-LIKE,)
• NCBI Gene ID: 151742
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5SGD2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase, Mg2+/Mn2+ dependent 1L interacts with:

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