- Gene Overview
- Interaction Network
- Sequence Verification
ADAMTS17, ADAM metallopeptidase with thrombospondin type 1 motif 17
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This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may promote breast cancer cell growth and survival. Mutations in this gene are associated with a Weill-Marchesani-like syndrome, which is characterized by lenticular myopia, ectopia lentis, glaucoma, spherophakia, and short stature. [provided by RefSeq, May 2016]
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Gene Synonyms (A disintegrin and metalloproteinase with thrombospondin motifs 17, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 17, WMS4,)
- NCBI Gene ID:
170691
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q8TE56
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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ADAM metallopeptidase with thrombospondin type 1 motif 17 interacts with:
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