FGD2, FYVE, RhoGEF and PH domain containing 2

FGD2, FYVE, RhoGEF and PH domain containing 2

• The protein encoded by this gene belongs to a family of guanine nucleotide exchange factors (GEFs) which control cytoskeleton-dependent membrane rearrangements by activating the cell division cycle 42 (CDC42) protein. This gene is expressed in B lymphocytes, macrophages, and dendritic cells. The encoded protein may play a role in leukocyte signaling and vesicle trafficking in antigen-presenting cells in the immune system. [provided by RefSeq, Oct 2016]

• Gene Synonyms (FYVE, RhoGEF and PH domain-containing protein 2, FGD1 family, member 2, FLJ00276 protein, epididymis secretory sperm binding protein, zinc finger FYVE domain-containing protein 4, ZFYVE4,)
• NCBI Gene ID: 221472
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q7Z6J4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

FYVE, RhoGEF and PH domain containing 2 interacts with:

• transmembrane protein 239

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.