FCGR3B, Fc fragment of IgG receptor IIIb

FCGR3B, Fc fragment of IgG receptor IIIb

• The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012]

• Gene Synonyms (CD16, CD16A, CD16b, FCG3, FCGR3, FCGR3A, FCR-10, FCRIII, FCRIIIb, low affinity immunoglobulin gamma Fc region receptor III-B, Fc fragment of IgG, low affinity IIIb, receptor (CD16b), Fc gamma receptor III-B, Fc gamma receptor IIIb, Fc-gamma receptor IIIb (CD 16), fc-gamma RIII-beta, fc-gamma RIIIb, igG Fc receptor III-1,)
• NCBI Gene ID: 2215
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A087WU90
  UNIPROT ID#>>O75015
  UNIPROT ID#>>M9MML6
  UNIPROT ID#>>A0A087WZR4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Fc fragment of IgG receptor IIIb interacts with:

• CCR4-NOT transcription complex subunit 8
  CD109 molecule
  ciliogenesis associated kinase 1
  cytochrome c oxidase assembly factor COX16
  dynein 2 intermediate chain 2
  glycerol kinase
  integrin subunit alpha V
  kelch like family member 20
  leucine rich repeat containing 8 VRAC subunit C
  leucine rich repeat containing 8 VRAC subunit E
  neuronal pentraxin 1
  neuropilin 2
  nuclear receptor subfamily 2 group F member 2
  out at first homolog
  tubulin alpha 1a
  tubulin beta 3 class III
  tubulin beta 8 class VIII

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.